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18 Overall, ALC was generally well tolerated, with predominantly mild GI and CNS events, and no evidence of excess serious AEs compared with controls
These findings strongly suggest that L-carnitine is available as a conventional therapy for cirrhosis-related sarcopenia and that its combined use with rifaximin has the potential to be a novel effective therapy
doi: 10.1038/s41467-022-28683-0 111 FriasJPNauckMAVanJKutnerMECuiXBensonCet al
It helps in the activation of an enzyme (GSH transferase B) that plays an important role in detoxification (4)
These data suggests there may be a sensor that sets the ELF GSH adaptive response to prevent GSH levels from dipping below basal levels
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